Lunzhi Dai Selected Research

CYD0618

11/2019

A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.

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Lunzhi Dai Research Topics

Disease

15	Neoplasms (Cancer) 05/2022 - 10/2014
4	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2019
2	COVID-19 01/2022 - 10/2020
2	Starvation 01/2021 - 01/2016
2	Bites and Stings (Sting) 01/2018 - 01/2018
1	Disease Progression 02/2022
1	Cognitive Dysfunction 02/2022
1	Lymphoma (Lymphomas) 01/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022
1	Brain Ischemia (Cerebral Ischemia) 01/2022
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022
1	Thyroid Neoplasms (Thyroid Cancer) 07/2021
1	Sarcopenia 01/2021
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2021
1	Lung Injury 01/2021
1	Insulin Resistance 01/2020
1	Infections 10/2019
1	Sepsis (Septicemia) 10/2019
1	Hypoxia (Hypoxemia) 10/2019
1	Non-alcoholic Fatty Liver Disease 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Fatty Liver 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Liver Diseases (Liver Disease) 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2019
1	Obesity 01/2019
1	Atherosclerosis 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Carcinogenesis 01/2018
1	Papillary Thyroid Cancer 01/2018
1	Virus Diseases (Viral Diseases) 01/2018
1	T-Cell Leukemia (Leukemia, T Cell) 10/2016
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2016
1	Epilepsy (Aura) 01/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2015
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 10/2014
1	Neuroblastoma 10/2014
1	Glutaric Acidemia I 04/2014

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2014
5	Histones (Histone)IBA 01/2022 - 10/2014
3	Long Noncoding RNAIBA 01/2019 - 01/2018
2	LipidsIBA 01/2022 - 01/2019
2	EnzymesIBA 12/2021 - 10/2020
2	RNA (Ribonucleic Acid)IBA 07/2021 - 01/2016
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2015
2	Phosphotransferases (Kinase)IBA 01/2020 - 01/2019
2	Antiviral Agents (Antivirals)IBA 01/2018 - 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2022
1	Retinaldehyde (Retinal)IBA 02/2022
1	Thrombin FDA Link 01/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	phosphatidylethanolamineIBA 01/2022
1	Cetuximab (Erbitux)FDA Link 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	Serine (L-Serine)FDA Link 12/2021
1	Indicators and Reagents (Reagents)IBA 07/2021
1	Epidermal Growth Factor (EGF)IBA 01/2021
1	Tryptophan (L-Tryptophan)FDA Link 01/2021
1	Branched-Chain Amino AcidsIBA 01/2021
1	Amino Acids FDA Link 01/2021
1	Isoleucine (L-Isoleucine)FDA Link 01/2021
1	Leucine (L-Leucine)FDA Link 01/2021
1	histone H3 trimethyl Lys4IBA 01/2021
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Concanavalin AIBA 01/2021
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2021
1	Synthetic Vaccines (Recombinant Vaccines)IBA 10/2020
1	VaccinesIBA 10/2020
1	AntibodiesIBA 10/2020
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 10/2020
1	Actins (F Actin)IBA 01/2020
1	Insulin (Novolin)FDA Link 01/2020
1	DiterpenesIBA 11/2019
1	oridoninIBA 11/2019
1	Kaurane DiterpenesIBA 11/2019
1	CYD0618IBA 11/2019
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 11/2019
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2019
1	Pyruvic Acid (Pyruvate)IBA 10/2019
1	S pombe hsp9 proteinIBA 01/2019
1	corylinIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Fatty AlcoholsIBA 01/2019
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2019
1	Pattern Recognition ReceptorsIBA 01/2018
1	Complementary DNA (cDNA)IBA 01/2018
1	PCI 34051IBA 10/2016
1	Streptozocin (Streptozotocin)FDA Link 01/2016
1	ChromatinIBA 01/2016
1	Malonyl Coenzyme A (Malonyl CoA)IBA 11/2015
1	Histone Deacetylase InhibitorsIBA 10/2014
1	Vorinostat FDA Link 10/2014
1	glutaric acidIBA 04/2014
1	glutaryl-coenzyme A (glutaryl-CoA)IBA 04/2014

Therapy/Procedure

3	Therapeutics 01/2022 - 11/2019
1	Oral Administration 01/2019